Supplementary Movie 6

Representative timelapse movie of WM1158 cells, treated with either a scrambled control siRNA or siRNA targeting LPP3, in a circular invasion assay. Scale bar in bottom right corner is 50μm.

LPP3 mediates self-generation of chemotactic LPA gradients by melanoma cells

Olivia Susanto, Yvette W. H. Koh, Nick Morrice, Sergey Tumanov, Peter A. Thomason, Matthew Nielson, Luke Tweedy, Andrew J. Muinonen-Martin, Jurre J. Kamphorst, Gillian M. Mackay, and Robert H. Insall

J Cell Sci 2017. 130:3455-3466; doi: 10.1242/jcs.207514