Movie 5

Co-depletion of MAD-1 and MAD-2 in multicellular Δnud2 embryos results in severe chromosome mis-segregation.Embryos (~32-cell stage) express GFP::histone H2B and GFP::γ-tubulin. Time lapse is 10 s and playback speed is 6 frames per second. Scale bar, 5 μm.

NudE regulates dynein at kinetochores but is dispensable for other dynein functions in the C. elegans early embryo

Patrícia A. Simões, Ricardo Celestino, Ana X. Carvalho, and Reto Gassmann

J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.212159