To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie-S3 A HeLa cell expressing GRPR and and PIP2 sensor (Venus-PH) shows profound PIP2 hydrolysis upon addition of 1 μM bombesin. Scale bar 10 mm. Melanopsin (Opn4) utilizes Gαi and Gβγ as major signal transducers Dinesh Kankanamge, Kasun Ratnayake, Saroopa Samaradivakara, and Ajith Karunarathne J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.212910 Download Original Video