Supplemental Movie 1

Dynamics of eGFP-tagged FGFR wild type and activating mutants in Ishikawa cells. Spinning disk confocal microscopy time-lapse images of Ishikawa cells stably expressing eGFP-tagged FGFR wild type (left panel), or activating mutants; N550K (middle panel), Y376C (right panel). Images were acquired every 2 seconds for 1 minute. The video plays at 10 frames s-1 and is thus accelerated 20 times

FGFR2-activating mutations disrupt cell polarity to potentiate migration and invasion in endometrial cancer cell models

Samantha J. Stehbens, Robert J. Ju, Mark N. Adams, Samuel R. Perry, Nikolas K. Haass, David M. Bryant, and Pamela M. Pollock

J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.213678