Movie S1

Flotillin 2 and MT1-MMP are colocalized in intracellular vesicles, at the PM and in endocytic vesicles.
Confocal images of flotillin 2-mCherry and MT1-MMP-GFP in MDA-MB-231 cells; 1 frame/15 seconds. White arrow indicates a MT1-MMT and flotillin 2-containing endocytic vesicle emerging from the PM. Scale bar: 1μm.

MT1-MMP targeting to endolysosomes is mediated by upregulation of flotillins

Damien Planchon, Eduardo Rios Morris, Mallory Genest, Franck Comunale, Sophie Vacher, Ivan Bièche, Evgeny V. Denisov, Lubov A. Tashireva, Vladimir M. Perelmuter, Stefan Linder, Philippe Chavrier, Stéphane Bodin, and Cécile Gauthier-Rouvière

J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.218925

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