Movie 4

Time lapse movie of a HUVEC layer expressing VE-cadherin-mCherry (red) and EGFP-p20 (green) stimlated wth thrombin. Note the thrombin-induced inhibition of JAIL, followed by the formation of an interrupted VE-cadherin pattern, which reconstitutes after the thrombin effect is inhibited endogenously. Orally annotated. (Seebach et al. 2015).