Movie 2

MDA-MB-231 cells were transfected with the indicated siRNAs. 24 h post transfection, cells were transfected with MT1-MMPpHluorin and replated onto collagen-coated TIRF dishes the next day. 24 h later, cells were imaged by TIRF live microscopy. Time in minutes, scale bar, 10 μm.

DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes

Bettina Noll, David Benz, Yannick Frey, Florian Meyer, Manuel Lauinger, Stephan A. Eisler, Simone Schmid, Peter L. Hordijk, and Monilola A. Olayioye

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.223172