Movie 2
MDA-MB-231 cells were transfected with the indicated siRNAs. 24 h post transfection, cells were transfected with MT1-MMPpHluorin and replated onto collagen-coated TIRF dishes the next day. 24 h later, cells were imaged by TIRF live microscopy. Time in minutes, scale bar, 10 μm.
DLC3 suppresses MT1-MMP-dependent matrix degradation by controlling RhoB and actin remodeling at endosomal membranes
J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.223172