Movie 6

(Top) Co-culture assay whereby HaCaT cells (green) are co-cultured with either NIH3T3 cells (left, magenta) or HT1080 cells (right, magenta). 10 min frames. Scale bar = 100 μm. (Bottom) Tracks of NIH3T3 fibroblasts (left) and HT1080 fibrosarcoma cells (right) from the movies above. Tracks shift blue to red throughout the movie to demonstrate that, in the HT1080 case (bottom right), cells become segregated from HaCaT cells (not labelled) over time.

Heterotypic contact inhibition of locomotion can drive cell sorting between epithelial and mesenchymal cell populations

Simon Brayford, Fiona N. Kenny, Toru Hiratsuka, Eduardo Serna-Morales, Lawrence Yolland, Andrei Luchici, and Brian M. Stramer

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.223974