Movie 5

PI3K2(KE)-Halo-TMR & RBD_Raf1-GFP/Ax2 (TIRF). Time-lapse TIRF images show PI3K2^{K857, 858E}-Halo-TMR (left), RBD_Raf1-GFP (center) and merged (right), corresponding to Fig. 3A.

Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells

Seiya Fukushima, Satomi Matsuoka, and Masahiro Ueda

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.224121

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