Movie 8

RBDRaf1-GFP (+100 μM LY294002). Time-lapse confocal images show RBDRaf1-GFP with 100 μM LY294002, corresponding to Fig. 4A. LY294002 was added at time 1 min. Scale bars represent 20 μm. Time format is “mm:ss”.

Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells

Seiya Fukushima, Satomi Matsuoka, and Masahiro Ueda

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.224121