To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 8 RBDRaf1-GFP (+100 μM LY294002). Time-lapse confocal images show RBDRaf1-GFP with 100 μM LY294002, corresponding to Fig. 4A. LY294002 was added at time 1 min. Scale bars represent 20 μm. Time format is “mm:ss”. Excitable dynamics of Ras triggers spontaneous symmetry breaking of PIP3 signaling in motile cells Seiya Fukushima, Satomi Matsuoka, and Masahiro Ueda J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.224121 Download Original Video