Movie 13

EM tomograms from fAS-stimulated microglial cells.
EM high-magnification (20000X) tomograms corresponding to the images indicated as Fig. 3A (Movie 10), Fig. 3B (Movie 11), Fig. 3E (Movie 12) and Fig. 3G (Movie 13) are shown as video files. Of note, the presence of double membrane autophagosomes.

Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells

Claudio Bussi, Javier M. Peralta Ramos, Daniela S. Arroyo, Jose I. Gallea, Paolo Ronchi, Androniki Kolovou, Ji M. Wang, Oliver Florey, Maria S. Celej, Yannick Schwab, Nicholas T. Ktistakis, and Pablo Iribarren

J Cell Sci 2018. 131:None-None; doi: 10.1242/jcs.226241