Movie 1

Related to Figure 1E. Time-lapse video of Tln1-/-Tln2-/- cells expressing the truncated talin proteins. Cells expressing different talin proteins were plated on a fibronectin-coated polystyrene plate and allowed to attach to the surface for 120 minutes before imaging. Time-lapse series was collected at a 360 seconds interval for 12 hours.

Talin-mediated force transmission and talin rod domain unfolding independently regulate adhesion signaling

Rolle Rahikainen, Tiina Öhman, Paula Turkki, Markku Varjosalo, and Vesa P. Hytönen

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.226514