Movie 9

Speckles fuse after chromatin barrier is depleted.
Corresponds to nucleus II in Fig. 7. SiR-Hoechst staining (red) with GFP-SON (green) after DRB treatment. Movie is a single optical section for each time point. Time(hr:min:sec) after DRB addition and scale bar are stamped on the movies.

Nuclear speckle fusion via long-range directional motion regulates speckle morphology after transcriptional inhibition

Jiah Kim, Kyu Young Han, Nimish Khanna, Taekjip Ha, and Andrew S. Belmont

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.226563