To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Play VideoPlayMuteCurrent Time 0:00/Duration Time 0:00Loaded: 0%Progress: 0%Stream TypeLIVERemaining Time -0:00 Playback Rate1ChaptersChaptersdescriptions off, selectedDescriptionssubtitles off, selectedSubtitlescaptions off, selectedCaptionsAudio TrackFullscreenThis is a modal window. Captions Settings Dialog Beginning of dialog window. Escape will cancel and close the window. Text Color White Black Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Opaque Background Color Black White Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Transparent Window Color Black White Red Green Blue Yellow Magenta Cyan Transparency Transparent Semi-Transparent Opaque Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Dropshadow Font Family Proportional Sans-Serif Monospace Sans-Serif Proportional Serif Monospace Serif Casual Script Small Caps Defaults Done Movie 6 4D intravital imaging of orthotopic xenograft tumor cell from Fig. 5A. MDA-MB-231-FUCCI-mCerulean3-Lifeact7 tumor cell in G1 (red nucleus) extends and retracts an actin-rich (cyan) protrusion. Images were acquired every 3 minutes for 30 minutes. Scale bar 10 μm. Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle Battuya Bayarmagnai, Louisiane Perrin, Kamyar Esmaeili Pourfarhangi, Xavier Graña, Erkan Tüzel, and Bojana Gligorijevic J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.227116 Download Original Video