Movie 1

This movie relates to the data in Fig. 2G and shows a TIRF microscopy recording of mCh-CHUtr (left; inverted) and GCaMP5G (right, green) fluorescence change in response to 11 mM glucose and subsequent addition, and later washout, of 250 μM diazoxide. The movie plays at 50 times real speed.

Cortical mitochondria regulate insulin secretion by local Ca2+ buffering in rodent beta cells

Nadine Griesche, Gonzalo Sanchez, Cedric Hermans, and Olof Idevall-Hagren

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.228544