Movie 3

PDGF-stimulated CDR formation and macropinocytosis in PIK3CB KO NIH3T3 cells. PIK3CB KO NIH3T3 cells were seeded in MatTek dishes and serum-starved overnight. Time lapse images were acquired at 1 frame/10 sec, for a total duration of 30 minutes. PDGF was added after 1 min. The replay speed is 3 min/s.

PI3Kβ is selectively required for growth factor-stimulated macropinocytosis

Gilbert Salloum, Charles T. Jakubik, Zahra Erami, Samantha D. Heitz, Anne R. Bresnick, and Jonathan M. Backer

J Cell Sci 2019. 132:None-None; doi: 10.1242/jcs.231639