Movie 3

Simulation corresponding to panels A and C of Fig. 8. Disruption of MT assembly decreases the association of dynein with MTs. Extensile forces decrease and the axon pulls the growth cone rearward.

Dynein-mediated microtubule translocation powering neurite outgrowth in chick and Aplysia neurons requires microtubule assembly

Kristi McElmurry, Jessica E. Stone, Donghan Ma, Phillip Lamoureux, Yueyun Zhang, Michelle Steidemann, Lucas Fix, Fang Huang, Kyle E. Miller, and Daniel M. Suter

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.232983

Download Original Video