Movie 1

500 ns simulation of the chimeric mutant Pb PfnPf Loop in grey compared to Plasmodium berghei profilin-WT (cyan) using all atom molecular dynamics simulation. The profilin mutant (or WT) is bound to Plasmodium berghei actin. For comparison, see movies in Moreau et al., 2017 (ref 5), for 150 ns simulations for mutants of the profilin arm.

A function of profilin in force generation during malaria parasite motility that is independent of actin binding

Catherine A. Moreau, Katharina A. Quadt, Henni Piirainen, Hirdesh Kumar, Saligram P. Bhargav, LĂ©anne Strauss, Niraj H. Tolia, Rebecca C. Wade, Joachim P. Spatz, Inari Kursula, and Friedrich Frischknecht

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.233775