Movie 2

Transmitted light images of an MDA-MB-231 spheroid showing invasion of cells with dynamically changing morphology into a 1 mg/ml collagen I gel. Images are taken every 5 minutes starting at t = 7.75 h after collagen embedding of the spheroid. Length of movie is 6.25 hours. Movie is played back at 7 frames/s. Frames from this movie are also shown in Fig. S1d and Fig. 2 in the main text. Scale bar = 25 μm.