Movie 6

MDA-MB-231 cell also shown in V4 shown over a longer time period starting immediately after completion of collagen gelation (t = 81 min after collagen embedding). The cell shows persistent attachment of collagen fibers at the site of multiple recurrent blebs (bracketed region). Images were taken every 10 seconds. Length of movie is 28.5 minutes. Movie is played back at 7 frames/s. Frames from this movie are also shown in Fig. 7B in the main text. Scale bar = 10 μm.

Delineating the role of membrane blebs in a hybrid mode of cancer cell invasion in three-dimensional environments

Asja Guzman, Rachel C. Avard, Alexander J. Devanny, Oh Sang Kweon, and Laura J. Kaufman

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.236778