Movie 2

Search and kill assays of cognate targets in the presence of Lck and Mek 1/2 inhibition
Live-cell imaging of LGO1 cells (green) co-embedded with cognate EL-4 tumour cells (blue) in a 3D collagen matrix over 12 h in the presence of vehicle (left), 10 μM Lck inhibitor (middle) and 5 μM Mek 1/2 inhibitor (right). Killed cells appear in pink (propidium iodide uptake). Time in h:min:s. Scale bar: 100μm

The Lifeact-EGFP mouse is a translationally controlled fluorescent reporter of T cell activation

Jorge Luis Galeano Niño, Szun S. Tay, Jacqueline L. E. Tearle, Jianling Xie, Matt A. Govendir, Daryan Kempe, Jessica Mazalo, Alexander P. Drew, Feyza Colakoglu, Sarah K. Kummerfeld, Christopher G. Proud, and Maté Biro

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.238014