Movie 1

Comparison of protrusion dynamics in control and Lpd-deficient B16-F1 cells. Phase-contrast movies of B16-F1 wildtype and Lpd knockout cells (Lpd KO#10) migrating on laminin. Note individual examples of Lpd knockout cells, the protrusion of which is characterized by a fluctuating, chaotic mode of lamellipodial dynamics (white arrows).