Movie 1

Comparison of protrusion dynamics in control and Lpd-deficient B16-F1 cells. Phase-contrast movies of B16-F1 wildtype and Lpd knockout cells (Lpd KO#10) migrating on laminin. Note individual examples of Lpd knockout cells, the protrusion of which is characterized by a fluctuating, chaotic mode of lamellipodial dynamics (white arrows).

Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation

Georgi Dimchev, Behnam Amiri, Ashley C. Humphries, Matthias Schaks, Vanessa Dimchev, Theresia E. B. Stradal, Jan Faix, Matthias Krause, Michael Way, Martin Falcke, and Klemens Rottner

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.239020