To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Play VideoPlayMuteCurrent Time 0:00/Duration Time 0:00Loaded: 0%Progress: 0%Stream TypeLIVERemaining Time -0:00 Playback Rate1ChaptersChaptersdescriptions off, selectedDescriptionssubtitles off, selectedSubtitlescaptions off, selectedCaptionsAudio TrackFullscreenThis is a modal window. Captions Settings Dialog Beginning of dialog window. Escape will cancel and close the window. Text Color White Black Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Opaque Background Color Black White Red Green Blue Yellow Magenta Cyan Transparency Opaque Semi-Transparent Transparent Window Color Black White Red Green Blue Yellow Magenta Cyan Transparency Transparent Semi-Transparent Opaque Font Size 50% 75% 100% 125% 150% 175% 200% 300% 400% Text Edge Style None Raised Depressed Uniform Dropshadow Font Family Proportional Sans-Serif Monospace Sans-Serif Proportional Serif Monospace Serif Casual Script Small Caps Defaults Done Movie 4 Phase contrast imaging of Hela cells treated with 5μM 1g + 2μM AZ3146 (Mps1 inhibitor). Experimental conditions identical to movie 3. A novel benzodiazepine derivative that suppresses microtubule dynamics and impairs mitotic progression Vittoria Pirani, Mathieu Métivier, Emmanuel Gallaud, Alexandre Thomas, Siou Ku, Denis Chretien, Roberta Ettari, Regis Giet, Lorenzo Corsi, and Christelle Benaud J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.239244 Download Original Video