Movie 1

DLC1 controls endothelial focal adhesion dynamics. Time lapse recording of HUVECs transduced with shControl or shDLC1 and expressing paxillin-mCherry. Images were acquired by time-lapse TIRF microscopy (NIKON Eclipse Ti) using a 60x/1.49 NA oil objective. Frames were taken every 30 sec for ~ 2,5 hours.

DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis

Miesje van der Stoel, Lilian Schimmel, Kalim Nawaz, Anne-Marieke van Stalborch, Annett de Haan, Alexandra Klaus-Bergmann, Erik T. Valent, Duco S. Koenis, Geerten P. van Nieuw Amerongen, Carlie J. de Vries, Vivian de Waard, Martijn Gloerich, Jaap D. van Buul, and Stephan Huveneers

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.239947

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