Cardiomyocyte differentiation of WT and LmnA-/- human ES cells.
Wild-type (top) H1 human embryonic stem cells, and LmnA-/- knockout (bottom) cells derived from the same line, are shown after 13 days (left) or 17 days (right) of treatment with KY02111 (see reference in Minami et al., 2012). Loss of Lamin A does not impede any aspect of this in vitro differentiation.