Movie 6

Representative time-lapse movie of arterial endothelial cell migrations during vasculogenesis of the dorsal aorta after knockdown of claudin-5a. Shown is the endothelial-specific line Tg(fli1:nEGFP)y7. White dots indicate single arterial endothelial cells. Images were acquired every 30 min over a total time of 7 h from 17 hpf to 24 hpf. Scale bar: 30 μm. Related to Fig. 4B.

The tight junction protein Claudin-5 limits endothelial cell motility

Zhenguo Yang, Shuilong Wu, Federica Fontana, Yanyu Li, Wei Xiao, Zhangdai Gao, Alice Krudewig, Markus Affolter, Heinz-Georg Belting, Salim Abdelilah-Seyfried, and Jingjing Zhang

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.248237