Movie 10

Restoring ER-mitochondrial tether rescue the migration defects in MFN2-deficient dHL-60 cells.
Chemotaxis of control, MFN2-deficient, and MFN2-deficient cells with synthetic tether construct towards fMLP in the μ-slide. Individual neutrophils in the left half of the chamber were tracked. Scale bar: 50 μm.