Movie 11

Rac inhibition restores chemotaxis in MFN2-deficient dHL-60 cells.
Chemotaxis of control and MFN2 knockdown cells treated with DMSO, NSC23766 (200 μM) or CAS 1090893 (50 μM) towards fMLP in the μ-slide. Individual neutrophils in the left half of the chamber were tracked. Scale bar: 50 μm.