Movie 6

Corresponding to Fig. 5g. APPL1 siRNA-treated cells expressing Lyn₁₁-RFP (white) imaged for plasma membrane ruffling every 20 sec during EGF treatment. EGF addition occurred between 120-140 sec timestamps, as indicated. Playback rate: 6 fps. Scale bar: 5 μm. Movie is representative of .30 movies from 4 separate experiments.