Movie 3.

Video of maximum intensity z-stack projections from time-lapse imaging of WT and KO oocytes expressing securin-EGFP (green), histone-H2B-mCherry (red, chromosomes) and stained with SiR-tubulin (cyan, microtubules) that were cultured in the presence of 0.5 μM PD0166285 (PD, WEE1/MYT1 inhibitor). Time (hh:mm) is relative to germinal vesicle breakdown (GVBD). The bar corresponds to 20 μm.

CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes

Ivana Ferencova, Michaela Vaskovicova, David Drutovic, Lucie Knoblochova, Libor Macurek, Richard M. Schultz, and Petr Solc

J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.252924