Movie 2
Mtb WT induces LC3-TVS formation. iPSDM expressing GFP-LC3B (green) were infected with E2Crimson Mtb WT (red) and followed by live cell confocal microscopy with frames every 5 min. Time 0 is the frame prior to phagocytosis. Movie is a maximum projection of 7 Z slices. Scale bar 5 μm, arrow indicates bacterium of interest. Presented at 10 frames per second. Stills from this movie are presented in figure 3.
M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion
J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.252973