Movie 3

Mtb ΔRD1 fails to induce LC3B recruitment to the bacteria or other membranes in the vicinity of the phagosome. iPSDM expressing GFP-LC3B (green) were infected with E2Crimson Mtb ΔRD1 (red) and followed by live cell confocal microscopy with frames every 5 min. Movie is a maximum projection of 8 Z slices. Scale bar 10 μm. Presented at 10 frames per second. Stills from this video are presented in figure 3.

M. tuberculosis infection of human iPSC-derived macrophages reveals complex membrane dynamics during xenophagy evasion

Elliott M. Bernard, Antony Fearns, Claudio Bussi, Pierre Santucci, Christopher J. Peddie, Rachel J. Lai, Lucy M. Collinson, and Maximiliano G. Gutierrez

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.252973