Movie 10.
PLP2-ZO-1 association contributes to PLP2 mediated collective cell migration. Phase-contrast images of migrating PLP2KO (left), PLP2KO cells overexpressing ΔNPLP2-mCherry (middle) and mCherry-PLP2ΔC (right); 1 frame/ 15 mins for 12 hrs. Scale bars: 50 μm.
PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells
J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.253468