Movie 6.

Intracellular and extracellular PLP2 plays a crucial role in collective cell migration. Phase-contrast images of migrating control, PLP2KO, PLP2KO cells overexpressing PLP2-mCherry and PLP2KO cells treated with exosomePLP2-GFP (respectively from left to right); 1 frame/ 15 mins for 12 hrs. Scale bars: 50 μm.

PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells

Dipanjana Ghosh, Ankita Dutta, Anjali Kashyap, Neeraj Upmanyu, and Sunando Datta

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.253468

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