Movie 7.

Exosomal PLP2 contributes to the collective migration. Phase-contrast images of migrating PLP2KO cells treated with exosome^SW480 (left), exosome^PLP2KO (middle) and exosome^PLP2-GFP (right); 1 frame/ 15 mins for 12 hrs. Scale bars: 50 μm.

PLP2 drives collective cell migration via ZO-1-mediated cytoskeletal remodeling at the leading edge in human colorectal cancer cells

Dipanjana Ghosh, Ankita Dutta, Anjali Kashyap, Neeraj Upmanyu, and Sunando Datta

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.253468

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