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Movie 2

Electron tomography and 3D reconstruction of a thick section from a chemically-fixed VAMP7+VAMP8 double knockout HeLa cell revealing ‘hourglass profiles’ of MVB's (cyan) connected via small fusion pores and tethers (green). Scale bar 100nm.

Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway

Luther J. Davis, Nicholas A. Bright, James R. Edgar, Michael D. J. Parkinson, Lena Wartosch, Judith Mantell, Andrew A. Peden, and J. Paul Luzio

J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.255463