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Visualization of the GFP-illuminated primary cilia membrane used to establish high-resistance seals necessary to record polycystin-2 channel current.

Disrupting polycystin-2 EF hand Ca2+ affinity does not alter channel function or contribute to polycystic kidney disease

Thuy N. Vien, Leo C. T. Ng, Jessica M. Smith, Ke Dong, Matteus Krappitz, Vladimir G. Gainullin, Sorin Fedeles, Peter C. Harris, Stefan Somlo, and Paul G. DeCaen

J Cell Sci 2020. 133:None-None; doi: 10.1242/jcs.255562

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