To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 2. No Rab7 tubulation without NGF. (A) Live-TIRF acquisition of MEF co-transfected with GFP-Rab7 and TrkA-RFP in the absence of NGF shows a lack of tubulating events. Tubular microdomains of Rab7-positive endosomes retrieve TrkA, a mechanism disrupted in Charcot–Marie–Tooth disease 2B Ronja Markworth, Vivian Dambeck, Lars Malte Steinbeck, Angeliki Koufali, Bastian Bues, Tal M. Dankovich, Carolin Wichmann, and Katja Burk J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.258559 Download Original Video