Movie 12.
ACTN4 eGFP transfected (green) ACTN4 knockdown MDA-MB-231 (MDA shAC#1 in 1.2 mg/ml collagen gels) and HT-1080 (HT shAC#1 in 1.5 mg/ml collagen gels) cells migrating in 3D collagen gels. Lines depict trajectories of individual cells.
α-Actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization
J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.258581