Movie 6.
Trajectories of MDA-MB-231 control (MDA shCTL) and ACTN4 knockdown (MDA shAC#1, MDA shAC#2) cells migrating through 1.2 mg/ml 3D collagen gels. Lines depict trajectories of individual cells.
α-Actinin-4 drives invasiveness by regulating myosin IIB expression and myosin IIA localization
J Cell Sci 2021. 134:None-None; doi: 10.1242/jcs.258581