Mitochondria specific activation of Rho detected with the dimericTomato-2xrGBD sensor. Spinning disk time lapse movie of a HeLa cells expressing FRB anchored to the mitochondria (not shown), FKBP-p63-DH (grey) and the dimericTomato-2xrGBD sensor (mpI-inferno) stimulated with 100 nM rapamycin. The time stamper represents min:s.
Eike K. Mahlandt, Janine J. G. Arts, Werner J. van der Meer, Franka H. van der Linden, Simon Tol, Jaap D. van Buul, Theodorus W. J. Gadella, and Joachim Goedhart
J Cell Sci
2021. 134:None-None; doi: 10.1242/jcs.258823