Movie 4.

Flotillin 2 and AXL colocalize in intracellular vesicles in tumor cells. One MDA-MBA-MB-231 cell that co-expresses flotillin1-HA, flotillin-2-Cherry and AXL-GFP was imaged by spinning disk confocal microscopy; 1 frame/0.8 s. Scale bar: 10 μm.

Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition

Mallory Genest, Franck Comunale, Damien Planchon, Pauline Govindin, Dune Noly, Sophie Vacher, Ivan Bièche, Bruno Robert, Himanshu Malhotra, Andreas Schoenit, Liubov A. Tashireva, Josefina Casas, Cécile Gauthier-Rouvière, and Stéphane Bodin

J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.259178

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