Movie 5.
SPHK2 is abundant in flotillin-positive late endosomes in MDA-MB-231 cells. Movie of the boxed area shown in figure 5C acquired by spinning disk confocal microscopy of one MDA-MB231 cell that co-expresses flotillin 1-mCherry and SPHK2-GFP (1 frame/s. Scale bar: 2 μm).
Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition
J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.259178