To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 1. Time-lapse imaging of a leader mobile (LM) cell transiently transfected with H2B-mEmerald and F-tractin-FusionRed, which has been confined down to ∼3 μm. Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments Sandrine B. Lavenus, Karl W. Vosatka, Alexa P. Caruso, Maria F. Ullo, Ayesha Khan, and Jeremy S. Logue J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.259493 Download Original Video