To view this video please enable JavaScript, and consider upgrading to a web browser that supports HTML5 video Movie 4. U-2OS cell expressing GFP-Lifeact (green) treated with MLL siRNA#1, corresponding to Figure 3G panel d is shown. Frame size is 186x130 μm and frame step is 5 s. Scale bar, 10 μm. MLL regulates the actin cytoskeleton and cell migration by stabilising Rho GTPases via the expression of RhoGDI1 Akash Chinchole, Kaisar Ahmad Lone, and Shweta Tyagi J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.260042 Download Original Video