Movie 1.
Kif18b moves MCAK and EB3 to the plus ends of growing microtubules Dynamic microtubules in the presence of 25 nM MCAK-GFP (green), 25 nM Kif18b-mRuby3 (red), 100 nM SNAP647-EB3 (blue) with 12 μM tubulin. Seeds were stabilized with taxol and GMPCPP.
Potent microtubule-depolymerizing activity of a mitotic Kif18b–MCAK–EB network
J Cell Sci 2022. 136:None-None; doi: 10.1242/jcs.260144