Movie 3.

(related to Fig. 6). Simultaneously recruitment of Sec16A and Sec24D into newly formed Sec bodies. Sec bodies in INS-1 cells co-transfected with Halo-Sec16A and YFP-Sec24D. Cells were preincubated with a permeable Halo-646 dye prior KRB treatment during imaging every 30 seconds for 30 minutes. Notice co-distribution of proteins in reorganized structures undergoing fusion events.

Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells

Wessel van Leeuwen, Dan T. M. Nguyen, Rianne Grond, Tineke Veenendaal, Catherine Rabouille, and Ginny G. Farías

J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.260294