Movie 3.
(related to Fig. 6). Simultaneously recruitment of Sec16A and Sec24D into newly formed Sec bodies. Sec bodies in INS-1 cells co-transfected with Halo-Sec16A and YFP-Sec24D. Cells were preincubated with a permeable Halo-646 dye prior KRB treatment during imaging every 30 seconds for 30 minutes. Notice co-distribution of proteins in reorganized structures undergoing fusion events.
Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells
J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.260294