Movie 1.
Abnormal interneuron migration in the absence of Rac1/Rac3 GTPases. Time lapse images of YPF+ interneurons from Rac1/Rac3 wt and Rac1/Rac3dmut E14.5 organotypic slices. Images were acquired every 3min, for up to 8h at the level of the corticostriatal boundary. Movie is shown in 10 frames per second (fps).
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons
J Cell Sci 2023. 136:None-None; doi: 10.1242/jcs.260373