Movie 3.
Lysosomal positioning in migrating interneurons upon Rac1/Rac3 ablation. Time lapse images of Rac1/Rac3wt and Rac1/Rac3dmut interneurons migrating from MGE explants, stained with the fluorescent dyes lysotracker Red DND and Hoechst. Images were acquired every 3 min for 4h. Movie is shown in 10 frames per second (fps).
Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons
J Cell Sci 2023. 136:None-None; doi: 10.1242/jcs.260373