Movie 4.

Live imaging of frustrated phagocytosis of HIV-1-infected macrophages. Time-lapse imaging of MDMs infected with HIV-1-GAG-iGFP-ΔENV-VSVG for 3 days and seeded over human IgG-coats coverslips. Whole cell projections are shown for the top and middle panels, along the z-axis (middle) or the y axis (top). The bottom panel (transmission channel) is a single z-slice. Scale bar = 20 μm.

Release of HIV-1 particles from macrophages is promoted by an anchored cytoskeleton and driven by mechanical constraints

Vasco Rodrigues, Sarah Taheraly, Mathieu Maurin, Mabel San-Roman, Emma Granier, Anaël Hanouna, and Philippe Benaroch

J Cell Sci 2022. 135:None-None; doi: 10.1242/jcs.260511